Focus on Women's and Men’s Health

Host: Ayse Tuba Kendi, MD Guest: A. Oliver Sartor, MD Prostate-specific membrane antigen (PSMA) is highly expressed on prostate cancer (PC) cells and can be detected in tumors using positron emission tomography imaging. Even though clinical features predict different stages of PC progression, the application of imaging to guide treatment is still evolving but gaining substantial evidence for the targeting of PSMA. With clinical research shifting paradigms for the treatment of metastatic castration-resistant prostate cancer (mCRPC), novel treatment options require adoption and effective application into clinical practice. PSMA has become an appealing target for diagnostic agents for imaging and therapeutic agents to treat mCRPC. Radionuclide emitters are being used for both cell surface expression of PSMA and the tumor microenvironment, and research has proven the therapeutic efficacy of PSMA-directed radioligand therapy (RLT). In this educational activity, two experts will examine the role and rationale for PSMA targeted therapies and diagnostics—jointly known as theragnostics—as a revolutionary new approach to treating patients with advanced prostate cancer and will evaluate clinical trial data for PSMA-targeted RLT.

Host: Paul Doghramji, MD Guest: Megan Arnot Menopause is an inevitable transition in every woman’s life, but what if engaging in a basic physiological need like sex could delay its onset? Researching this potential connection is Megan Arnot, a Ph.D. candidate in the Department of Anthropology at the University College London. As the lead author of the study, she walks us through her findings and the range of factors they investigated, like the type of sexual activity and whether or not women lived with a partner.

Host: Jennifer Caudle, DO Guest: Frank LoVecchio, DO, MPH, FACEP Guest: Casey Lafferty, DO Due to the high prevelance of influenza each winter, knowing how to treat those most at risk is essential. That's why Dr. Frank LoVecchio and Dr. Casey Lafferty are here to discuss the 2019-2020 flu season activity and patterns, along with preventive tips and treatment options you can provide to your patients.

Host: Jennifer Caudle, DO Guest: Frank LoVecchio, DO, MPH, FACEP The cold weather inevitably brings an increase in flu cases each year, and joining Dr. Jennifer Caudle to unveil the high-risk populations—and how we can treat the members of those vulnerable populations who do get the flu—is Dr. Frank LoVecchio, Professor of Emergency Medicine at the University of Arizona and Principal Investigator for the Infectious Disease Network.

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Guest: Sheryl A. Kingsberg, PhD Guest: Brooke M. Faught, DNP, WHNP-BC,NCMP, IF Guest: Risa Kagan, MD, FACOG, CCD, NCMP Guest: James A. Simon, MD, CCD, NCMP, IF, FACOG An average of 37.5 million menopausal women in the US between the ages of 45 and 64 experience symptoms such as hot flashes and joint pain, but there are other symptoms that we rarely talk about: symptoms like vaginal dryness and dyspareunia. Featuring a patient and a panel of experts, this discussion reviews strategies that can be used to help patients feel comfortable in bringing up their struggles with menopause along with how we can help relieve women from their pain. ©2019 NP-INR-US-00214 09/19

Host: Amy Mackey, MD Guest: Maria Trent, MD, MPH, FAAP, FSAHM Even though molecular assays are quickly becoming the standard of care for the diagnosis of Mycoplasma genitalium and other infectious conditions, there’s still much more to be shared and learned about how to rapidly identify this infection. And here to start that discussion is Dr. Maria Trent, Professor of Pediatrics in the Division of General Pediatrics and Adolescent Medicine at Johns Hopkins School of Medicine. Click here to learn more about other women's health programs in this special series.

Host: Mario R. Nacinovich, Jr., MSc Guest: Kara Rood, MD A recent study following 346 pregnant patients found that 63 percent of the women were admitted into the hospital for uncertain diagnosis or delivery—all because preeclampsia has many of the same symptoms of other diseases. The good news, however, is that there’s a new test currently underway that could make the diagnosis and treatment of preeclampsia easier in order to prevent potentially dangerous outcomes for the mother and baby, as OB/GYN Dr. Kara Rood explains.

Host: Scott Kopetz, MD, PhD, FACP Guest: Alberto Sobrero, MD Guest: Rui-Hua Xu, MD El cáncer colorrectal metastásico es difícil de tratar y presenta varias mutaciones genéticas, expresiones y amplificaciones, tal como la lateralidad del tumor. Y, tal como explican el Dr. Scott Kopetz, el Dr. Rui-Hua Xu y el Dr. Alberto Sobrero, aunque identificar estas distinciones puede resultar una tarea difícil, al hacerlo se averiguan pistas esenciales para decidir cuál es la mejor opción de tratamiento para cada paciente.

Host: Scott Kopetz, MD, PhD, FACP Guest: Alberto Sobrero, MD Guest: Rui-Hua Xu, MD O cancro colorretal metastático é difícil de gerir e tem múltiplas mutações genéticas, expressões e amplificações, tais como o lado do tumor. E, apesar dos desafios em identificar estas distinções, estas também oferecem pistas essenciais sobre qual a melhor opção de tratamento para cada doente, tal como explicam o Dr. Scott Kopetz, o Dr. Rui-Hua Xu e o Dr. Alberto Sobrero.

Host: Scott Kopetz, MD, PhD, FACP Guest: Alberto Sobrero, MD Guest: Rui-Hua Xu, MD Metastatic colorectal cancer is difficult to manage and has multiple genetic mutations, expressions, and amplifications, such as tumor sidedness. And while identifying these distinctions can be challenging, they offer essential clues to which treatment option is best for each patient, as Dr. Scott Kopetz, Dr. Rui-Hua Xu, and Dr. Alberto Sobrero explain.

Guest: Edward J. Mayeaux, Jr., MD, DABFP, FAAFP In August 2018, the U.S. Preventive Services Task Force (USPSTF) released a final recommendation statement on cervical cancer screening for women of varying ages. This short animated video will tell you what you need to know about these recommendations, and how best to put them into daily practice.

With the number of women seeing their OB/GYN steadily declining year after year, who’s protecting them from serious health threats like STIs? That’s where primary care providers come in. Take a look to see how your practice can be part of the movement.

Host: Keith Isaacson, MD Guest: Robert K. Zurawin, MD This activity will discuss approaches that enable physicians to perform hysteroscopic surgery more safely and effectively by focusing on best practices, overcoming operative difficulties, and the inclusion of pharmacologic agents that improve visualization, reduce vascularity, and lower the possibility of hyponatremia.

Host: Robert K. Zurawin, MD Guest: Mary Johnston, BSN, RNFA, CNOR Guest: Charles E. Miller, MD, FACOG This activity will discuss the most significant changes in both in-office and outpatient hysteroscopic procedures, especially those which have resulted in the need to reappraise the parameters of fluid absorption.

Host: Robert K. Zurawin, MD Guest: Malcolm G. Munro, MD This activity will discuss the numerous elements that make up the updated diagnostic and treatment algorithm to manage abnormal uterine bleeding, including using a minimally invasive surgical approach, having a better understanding of the broad umbrella of bleeding that occurs outside of normal cyclic menstruation, performing proper patient workups, and more.

Host: Amy Mackey, MD Guest: Kirsten Sasaki, MD To help you ensure the safe and effective use of tissue morcellation during hysteroscopic and abdominal procedures, this activity will focus on the guidelines, evolutions in the procedure, and the risks versus benefits of adopting this technique.

Host: Jennifer Caudle, DO Guest: Michael G. Ross, MD, MPH Guest: Michael S. Ruma, MD, MPH Preterm birth not only causes steep medical costs, but it also has a significant impact on the child and family, resulting in both short-term and long-term complications like neurocognitive delays and growth impairments. This activity will explore the use of fetal fibronectin (fFN) as a marker for women who are at an increased risk of a preterm birth.

Host: Matt Birnholz, MD Guest: Robert S. Brown, Jr., MD, MPH Thrombocytopenia, or low platelet count, is the most frequent hematologic complication of chronic liver disease, and its impact can be devastating on patient care. Due to the risk of bleeding, patients with thrombocytopenia are blocked from receiving crucial invasive therapeutic and diagnostic procedures, which affects those with severe disease the most. This leads to questions on how to best manage thrombocytopenic patients with chronic liver disease. This activity will discuss recent advances in therapeutic options for patients with severe thrombocytopenia caused by chronic liver disease.

Host: Renée Simone Yolanda Allen, MD, MHSc., FACOG Guest: Amy Clouse, MD The primary care physician is the first line of defense when it comes to cervical cancer screening, and the need for physicians to be alert to their patients’ screening schedules is growing as fewer patients see their OB/GYN regularly. Tune in as Dr. Amy Clouse, Associate Director of the Family Medicine Residency Program at Abington-Jefferson Health, dives into the big questions, like what do we need to know about cervical cancer screening and how can we have a more active role in this testing?