JACC: Clinical Electrophysiology

At ACC.26, Dr. Tharshini Ramalingam speaks with JACC: CardioOncology Editor-in-Chief Dr. Bonnie Ky about the rapid evolution of cardio-oncology, the field's most urgent priorities, and the need for stronger evidence, risk prediction, cardioprotective strategies, and global implementation. Dr. Ky also shares practical advice for early-career investigators on mentorship, resilience, and what makes a manuscript impactful, rigorous, and truly additive to the field.

At ACC.26, Dr. Tharshini Ramalingam speaks with JACC: CardioOncology Editor-in-Chief Dr. Bonnie Ky about the rapid evolution of cardio-oncology, the field's most urgent priorities, and the need for stronger evidence, risk prediction, cardioprotective strategies, and global implementation. Dr. Ky also shares practical advice for early-career investigators on mentorship, resilience, and what makes a manuscript impactful, rigorous, and truly additive to the field.

Dr. Kenneth Ellebogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses the long-term outcomes and safety of His-Purkinje conduction system pacing: a multicenter observational study in China.

Deputy Editor Francis Marchlinski hosts a deep‑dive discussion on the study "Functional Conduction Block During Extra‑Stimulus Mapping Masks Deceleration Zones and Reveals Additional VT Substrate." In this episode, Dr. Marchlinski explores how extra‑stimulus pacing can alter the visualization of critical conduction deceleration zones and uncover previously hidden components of the ventricular tachycardia substrate. He breaks down the clinical implications of these dynamic changes and what they mean for improving VT mapping and ablation strategies.

Deputy Editor Kenneth Ellenbogen hosts a focused discussion on the study "Return‑to‑Play for Athletes with Desmosomal Arrhythmogenic Cardiomyopathy: A Single Center Experience." In this episode, Dr. Ellenbogen examines how desmosomal arrhythmogenic cardiomyopathy impacts athletic participation and highlights real‑world insights from a single‑center cohort. He walks listeners through the clinical considerations, risk assessment strategies, and decision‑making frameworks that guide safe return‑to‑play recommendations for competitive athletes. This conversation offers valuable perspective for clinicians navigating the balance between athletic performance and long‑term cardiovascular safety.

In this episode of JACC: Clinical Electrophysiology, Deputy Editor Dr. Kenneth Ellenbogen discusses His-Pacing versus Biventricular Pacing for Cardiac Resynchronization Therapy: Long-term follow-up from the His-alternative I Trial.

Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Dr. Volter Rudolph, discuss a recently published original research paper examining the frequency and outcomes of acute hemodynamic instability following tricuspid interventions.

Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Dr. Charles Davidson, discuss a recently published original research paper studying the transcatheter tricuspid valve intervention risk scores.

In this episode, Dr. Kenneth Ellenbogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses new long-term findings from the His-Alternative I trial, the first European randomized study comparing His-bundle pacing with conventional biventricular pacing for cardiac resynchronization therapy (CRT). He highlights five-year outcomes demonstrating that when His-bundle pacing is achieved with low implant thresholds, its long-term performance—including lead stability, generator replacements, and clinical response—closely mirrors that of biventricular CRT. Dr. Ellenbogen explores the implications of these results for contemporary conduction system pacing practice, the importance of strict implant criteria, and how these data help refine patient selection and procedural strategy in CRT.

Audio Summary of the April 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Shinichi Shirai.

Commentary by Dr. Shujuan Yang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.