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Specimen labeling errors have long plagued the laboratory industry, putting patients at risk of transfusion-related death, medication errors, misdiagnosis, and patient mismanagement.

In the early ‘90s, a group of scientists were screening peptides from a pheochromocytoma for biological activity.

Cardiac troponin is the preferred biomarker for detection of myocardial injury, and in the United States, laboratories are currently using fourth generation immunoassays.

Immunoglobulins are produced by the body in response to foreign substances such as bacteria and viruses, in order todestroy them.

Immunoglobulins are produced by the body in response to foreign substances such as bacteria and viruses, in order todestroy them.

The use of point of care testing in outpatient clinics and doctors’ offices for patient management decisions is becoming more common.

The use of point of care testing in outpatient clinics and doctors’ offices for patient management decisions is becoming more common.

Of the approximately 14 million blood donations performed every year in the US, it is estimated that as many as 140000 donations each year are unknowingly from sickle cell trait (HbAS)2 donors (1).

Biochemical prenatal screening tests are used to determine the risk of fetal aneuploidy based on the concentration of several biomarkers. The concentration of these biomarkers could be affected by preanalytical factors (PAFs) such as sample type (whole blood vs serum), storage time, and storage temperature. The impact of these factors on posttest risk is unknown.

SAn antinuclear antibody (ANA) testing strategy involving enzyme immunoassay (EIA) screening that reflexed to immunofluorescence assay (IFA) was implemented, monitored, and optimized for clinical utility.

Some posit that any amount of myocardial ischemia can be detected by high-sensitivity cardiac troponin assays. We hypothesized that patients with myocardial ischemia induced by exercise stress would have significantly higher increases in high-sensitivity cardiac troponin T (hs-cTnT) concentrations than patients without ischemia.

The objective of this reflection is to share thoughts about communication and collaboration with the healthcare team outside the laboratory to deal with such issues.

The aim of this survey was to investigate how well heart failure (HF) guidelines for use of natriuretic peptides (NPs) have been implemented in laboratory practice in Europe and North America.

Delta checks were first described in 1974 by Nosanchuk and Gottmann as a means to improve QC in clinical laboratories (1).

The fundamental role of the clinical laboratory is to provide accurate test results, thus guiding patient care when clinical history and physical exam are insufficient. It is no wonder then that, when test results are called into question, it can lead to anxiety and mistrust of the laboratory on the part of both clinicians and patients.

A sexually active 50-year-old woman with a history of hypothyroidism and a family history remarkable for cancer presented to her primary care physician with complaints of constipation and abdominal cramping.

Here we present a systematic review that was conducted to assess the use of nontraditional lipid biomarkers including apo B, apo A-I, apo B/A-I ratio, and non-HDL-C in improving CVD risk prediction after controlling for the traditional risk factors in populations at risk for cardiovascular events.

Our careers in clinical biochemistry started in Argentina, our native land. While we could not yet know that we would meet later in life thanks to our involvement with the AACC, our mutual passion for laboratory medicine was first ignited while exploring different healthcare career options near the end of high school.

This study revisits the utility of ?-glutathione S-transferase (?-GST) as a biomarker for acute liver injury in comparison to aspartate aminotransferase (AST) or alanine aminotransferase (ALT), the classic liver injury biomarkers.

In most healthcare settings, pregnancy testing is performed using urine, but urine testing has been shown to give false negative results in certain patients.