You Won Science: An Orphan Black Podcast

Orphan Black has been telling us we have to go back...so we're reviewing the science of Seasons 1 & 2: Neolutionism, stem cells, and more. This is the first of three parts, and we'll be releasing them while covering Season 4. ______________________________________________________________________     Crib notes for Season 4:Read about Donna Haraway, and Cosima Herter's essay about how Haraway's work influences Orphan Black: http://www.bbcamerica.com/shows/orphan-black/blog/2016/04/eat-medrink-me-and-the-trouble-with-cyborgs: Eat Me/Drink Me and the Trouble with CyborgsFind us at: Twitter: @You_Won_Science Facebook: facebook.com/youwonsciencepodcast Gmail: youwonscience@gmail.com www.youwonscience.com

We're talking about S1E3: How do you solve a problem like Dead Katja? What's the best approach for babysitting? And how hard is self-surgery post-rebar impalement? Also, we'll give a brief history of fingerprints, and answer the question of whether clones would indeed have identical ones. _______________________________________ Show Notes The History of Fingerprints Beavan, Colin. 2001. Fingerprints: The Origins of Crime Detection and the Murder Case that Launched Forensic Science. New York: Hyperion. (Book that emphasizes Faulds’ role, and really hates Galton.)   Galton.org: Victorian polymath: geographer, meteorologist, tropical explorer, founder of differential psychology, inventor of fingerprint identification, pioneer of statistical correlation and regression, convinced hereditarian, eugenicist, proto-geneticist, half-cousin of Charles Darwin and best-selling author. (Contains all of Galton’s work on fingerprinting, as well as scans of the Nature letters from Herschel, Faulds and Galton. Thinks Faulds was a nobody whiner.)   The forgotten pioneers of fingerprint science, G. S. Sodhi and Jasjeet Kaur, Current Science, 2005. (PDF) http://www.iisc.ernet.in/currsci/jan102005/185.pdf(Tells the stories of Haque’s and Bose’s contributions to the fingerprint classification system commonly known as the Henry System.)   Adermatoglyphia: The Genetic Disorder Of People Born Without Fingerprints, Joseph Stromberg, smithsonian.com, January 14, 2014. http://www.smithsonianmag.com/science-nature/adermatoglyphia-genetic-disorder-people-born-without-fingerprints-180949338/?no-ist   The Claim: Identical Twins Have Identical Fingerprints. By ANAHAD O'CONNORNOV. 2, 2004, The New York Times http://www.nytimes.com/2004/11/02/health/the-claim-identical-twins-have-identical-fingerprints.html?_r=0 WikipediaFingerprint https://en.wikipedia.org/w/index.php?title=Fingerprint&oldid=704300924 The Sepoy Rebellion/Indian Rebellion of 1857https://en.wikipedia.org/wiki/Indian_Rebellion_of_1857 ---------------------------------------------- You can find us at: Twitter: @You_Won_Science Facebook: www.facebook.com/youwonsciencepd/ Email us at hey@youwonscience.com Ask us questions! Tell us things! Please consider leaving us a review at iTunes, and thanks for listening!

Episode 2 of our Spoiler Free Rewatch ramps up the drama, and brings Sarah Manning within striking distance of the answers she's been seeking. Little does she know, it just gets weirder from here.    

Now that the Season 4 teasers have come out, it's time to rewatch Orphan Black until the April premiere! Join us for our Spoiler Free Episodes to tide you over until then.  This episode covers Season 1, Episode 1: Natural Selection, or Welcome Home, Sarah Manning! _____________________________________________________________________ Show Notes Charles Darwin Online: http://darwin-online.org.uk On the Origin of Species By Means of Natural Selection, &c.:  http://darwin-online.org.uk/EditorialIntroductions/Freeman_OntheOriginofSpecies.html EvoWiki: Discussion of Darwin and Racismhttp://evolutionwiki.org/wiki/Darwin_himself_was_racist Wikipedia: Scientific Racismhttp://en.wikipedia.org/wiki/Scientific Racism _____________________________________________________________________ Twitter: @you_won_science Facebook: http://www.facebook.com/youwonsciencepd http://youwonscience.com  

Waiting for the return of Orphan Black is hard. We want to help.This is the first part of our survival series, offering shows to watch when you're not rewatching (Orphan Black.)NOTE: Episode 10B will be the first in our Rewatch series, covering Season 1, Episode 1: Natural Selection. Show Notes:Wired: Is Sense8 Too Radical For Critics? Dark Angel — Official FOX Trailer (2000) https://www.youtube.com/watch?v=P8kkHMJyOYI   Utopia Trailer Channel 4 UK (2013) https://www.youtube.com/watch?v=r3gxwIqqzB4   Sense8 Trailer — Netflix (2015) https://www.youtube.com/watch?v=iKpKAlbJ7BQ   Mr Robot Trailer — USA https://www.youtube.com/watch?v=Ug4fRXGyIak   Humans Trailer — AMC https://www.youtube.com/watch?v=eb2RTxKnmn8    

In which we deal with our sadness at the end of Season 3, discuss the etymology of "neolution", talk about what our plans for the off-season are (hint: biweekly episodes, a rewatch of the series and the science never stops) and give a few more candidates for Season 4 episode title sources.____________________________________   Things we mention in the episode:Anti-Intellectualism in American Life : Richard Hofstadter The Immortal Life of Henrietta Lacks : Rebecca Skloot The Tuskegee Syphillis Experiment   _____________________________________   Say hello. Ask us things. Tell us things. youwonscience.comEmail: hey@youwonscience.com Facebook: You Won Science: An Orphan Black Podcast Tumblr: youwonsciencepodcast.tumblr.com Thank you for listening.

In which we wonder about why John Sadler had to die, discuss how hard it was to watch S03E09, and then explain mosaicism, chimerism and why mothers always have their children close to their internal organs. Also: Shout outs to Tatiana is Everyone and Science Vs. Hollywood. Enjoy the finale! _______________________________________CSI Chimera Episode and Blaschko’s Lines:http://genetics.thetech.org/ask/ask75     Chimeras, Mosaics and Other Fun Stuff: http://genetics.thetech.org/genetic-categories/chimeras-mosaics-and-other-fun-stuff     Blood Group Chimerism In Human Multiple Births Is Not Rare: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.149.9001&rep=rep1&type=pdf (PDF File) “Pregnancy may thus establish a long-term, low-grade chimeric state in the human female.” Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC40117/   Y-chromosome DNA Is Present in the Blood of Female Dogs Suggesting the Presence of Fetal Microchimerism: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068114 (open access) Tatiana is Everyone: An Orphan Black Podcast Science Vs Hollywood Twitter:@You_Won_Science Web: youwonscience.com Tumblr: youwonsciencepodcast.tumblr.com Facebook: You Won Science: An Orphan Black Podcast  

In which we briefly consider why Cosima hates to be the patient and whether the next faction hails from Cambridge, MA, then give you a crash course in proteins, prions and biochemistry. There will not be a test, but there are some handouts if you want them: Conspiracy Maps: Leda Clones & Castor Clones   Proteins and Prions: UCSF Medical Center   Prions: On The Trail of Killer Proteins   Wikipedia: Prion   Stanley Pruisner's Nobel Lecture on Prions   Also, if you have a suggestion for the source of next season's episode titles, let us know. The poll will be available on our website and Facebook Page on Monday June 15th.http://www.youwonscience.com__________________________ Email us at: hey@youwonscience.com Tumblr: youwonsciencepodcast.tumblr.com Facebook: You Won Science: An Orphan Black Podcast Twitter: @You_Won_Science

Episode 005 - Chekhov's Uterus In which we review Season 3, Episode 7 Community of Dreadful Fear and Hate and use Chekhov's Gun as a somewhat strained device to link Donnie's menstrual flow monitoring, Cosima's relapse, Shay's (possibly triggering) smoothies, and why you don't want to check your urine for misfolded proteins. Next episode: Misfolded Proteins and Prions, Oh My. Links: Learn more about histology and epithelium at: http://www.histology-world.com/contents/contents.htm#epithelium  More advanced information at: http://medcell.med.yale.edu/histology/epithelia_lab.php Excellent overview of endometriosis: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072685/  _______________________________________________________________Subscribe to us in iTunes!: http://apple.co/1Jg0LNSTwitter: @You_Won_ScienceTumblr: youwonsciencepodcast.tumblr.comFacebook: You Won Science: An Orphan Black PodcastEmail us at hey@youwonscience.comThank you for listening!

Episode 004: Paul is Dead Now, Miss Him, Etc. Show Notes This episode is brought to you by Mercury Retrograde. Drive one today! In which we miss Paul, wonder aloud about clones and dominant handedness, and begin a longer conversation (to be picked up in the next non-episode episode) about proteins, prions and disease. Alchemical symbols (as seen in The Island of Dr. Moreau and the Blue Period paintings of Rachel Duncan): http://alchemicaldiagrams.blogspot.com/2011/10/alchemy-symbols-with-meanings.html Genes and Handedness http://www.geneticliteracyproject.org/2014/12/02/left-handedness-genes-and-a-matter-of-chance/ HOMEWORK! If you’re interested in boning up before Episode 6 - Misfolded Proteins and Prions, Oh My! here is an article to start reading. It’s a good overview with introductory material. Protein Misfolding and Neurodegenerative Diseases http://www.nature.com/scitable/topicpage/protein-misfolding-and-degenerative-diseases-14434929 ____ You can find us at: Website: http://youwonscience.com Twitter: @You_Won_Science Facebook: You Won Science: An Orphan Black Podcast Page Tumblr: youwonsciencepodcast.tumblr.com   Subscribe on iTunes: http://apple.co/1Jg0LNS Thanks for listening!

In which I recap how Dyad's Rachel got where she is, both morally and physically, look at whether it could really happen like that, her prognosis (fictional and otherwise) and some bonus related scientific history. (If you're not current with Orphan Black, you should go away and please come back so you don't hate me.) You can subscribe in iTunes here if you'd like.__________________________________________Show Notes: Episode 003 – They Saved Rachel’s Brain? Physics Force Diagrams with Measurements used can be found at  http://www.youwonscience.com/2015/05/27/ep003_shownotes2/Projectile Motion Equations:http://www.physicsclassroom.com/class/vectors/Lesson-2/Horizontally-Launched-Projectiles-Problem-Solving Projectile Motion Simulation (with bonus Buick and Michelangelo statue)https://phet.colorado.edu/en/simulation/projectile-motion Inelastic Collision Calculator:http://hyperphysics.phy-astr.gsu.edu/hbase/inecol2.html Transorbital Intracranial Injuries: Transorbital penetrating Brain Injury imageshttp://radiopaedia.org/cases/transorbital-penetrating-brain-injuryS Matsumoto, K Hasuo, A Mizushima, F Mihara, M Fukui, T Shirouzu, and K MasudaIntracranial penetrating injuries via the optic canal.Am J Neuroradiol 1998 19: 1163-5http://www.ajnr.org/content/19/6/1163.longDaniel M. Bursick, Robert G. Selker.Intracranial pencil injuries.Surgical Neurology, Volume 16, Issue 6, December 1981http://dx.doi.org/10.1016/0090-3019(81)90235-4.(NOTE:Article is paywalled: boo.)http://www.sciencedirect.com/science/article/pii/0090301981902354Frontal Lobe: Functions and Injuries http://en.wikipedia.org/wiki/Frontal_lobeThe Centre for Neuro Skills | Brain Injury | Frontal Lobeshttp://www.neuroskills.com/brain-injury/frontal-lobes.php Neuropsychology (For samples of graded naming tests)http://www.slideshare.net/monipoli/neuropsychology-compiled-reportPhineas Gage http://en.wikipedia.org/wiki/Phineas_Gage Phineas Gage: Neuroscience's Most Famous Patienthttp://www.smithsonianmag.com/history/phineas-gage-neurosciences-most-famous-patient-11390067/?no-ist Isaac Newton Sticking Things in His Eye http://www.lib.cam.ac.uk/exhibitions/Footprints_of_the_Lion/8Bodkin.html (from his notebook) http://thegruesomeblog.com/2014/07/27/isaac-newton-his-eye-and-his-bodkin/ (if you want to see a bodkin)   http://www.baumanrarebooks.com/blog/the-story-behind-opticks-by-sir-isaac-newton/ ------------------------------------------------------------------You can find us at: http://www.youwonscience.com Facebook: You Won Science: An Orphan Black Podcast page Tumblr: http://youwonsciencepodcast.tumblr.com Twitter: @You_Won_ScienceEmail us with feedback, questions, corrections or  anything else that comes to mind at hey@youwonscience.comThank you for listening!

In which we introduce our approximately 90 second audio summary, discuss the many questions raised by the episode, the few answers given, speculate wildly and deal with how lesbians get over breakups. (Spoilers, obvs. So if you haven't seen "Scarred By Many Past Frustrations" go away and come back when you have.) Episode 3 out on Thursday: We Saved Rachel’s Brain! or Take Me to the Cyclops. Follow us on Twitter: Podcast: @You_Won_Science Liz Tracey: @liztracey Website: http://www.youwonscience.com Tumblr: http://youwonsciencepodcast.tumblr.com Facebook: You Won Science: An Orphan Black PodcastPlease send comments, questions, ideas, feedback, jokes, and dating advice to hey@youwonscience.com.Thank you, as always, for listening!    

In which I briefly discuss the mythology of the Leda/Zeus family, then conjecture wildly about what I'm calling the Helen Hypothesis, using relevant sound clips. Show Notes: Episode 1 Leda and the Swan(Man) Bullfinch’s Mythology: Full Text:http://www.sacred-texts.com/cla/bulf/ Theseus-Daedelus-Castor and Pollux: http://www.sacred-texts.com/cla/bulf/bulf19.htm The Trojan War: http://www.sacred-texts.com/cla/bulf/bulf26.htm Classical Source Material on Leda, Queen of Sparta http://www.theoi.com/Heroine/Leda.html Wikipedia: Leda and the Swan: http://en.wikipedia.org/wiki/Leda_and_the_Swan Castor and Pollux: http://en.wikipedia.org/wiki/Castor_and_Pollux Size of the Human Genome:http://www.ncbi.nlm.nih.gov/books/NBK21134/#A5276 Short Tandem Repeats and Familial Relationships: http://www.cstl.nist.gov/strbase/pub_pres/OConnor_USCIS_interpretation%20of%20DNA.pdf (This is a PDF of a PowerPoint presentation explaining how one assesses familial relationships via STR testing) Also:http://en.wikipedia.org/wiki/DNA_profiling#STR_analysis _______________________________________________Follow us on Twitter: @You_Won_ScienceWebsite: http://youwonscience.com Email comments, questions, concerns, jokes, etc. to hey@youwonscience.com  Thank you for listening!  

In episode 0 of You Won Science: An Orphan Black Podcast, I introduce myself and tell you a bit about why I'll be hopping the already moving bandwagon to talk about Orphan Black. The TL;DL version: I've been in a PhD program studying genetics and am pretty much the East Coast butch Cosima. I feel strongly that Orphan Black is not just great, smart entertainment, but an opportunity for people to discuss the larger issues in play, as well as learn more about molecular biology (i.e., it's a science gateway drug.)New episodes Mondays and Thursdays during the season, then moving to weekly after the finale.You can follow us at:Twitter: @You_Won_ScienceFacebook: facebook.com/YouWonScienceQuestions/concerns/suggestions can be sent to us at hey@youwonscience.com.Thanks for listening!