Science Signaling Podcast

Science Signaling Podcast for 25 October 2016: How glucocorticoids stimulate fat

Brian Feldman explains how a secreted protease inhibits diet- and glucocorticoid-induced...

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Science Signaling Podcast for 18 October 2016: ALK combination therapies for lung cancer

Eric Haura describes the identification of new targets for treating lung cancers driven by ALK...

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Science Signaling Podcast for 13 September 2016: DMF and the immune system

Benjamin Cravatt, John Teijaro, and Megan Blewett describe how the immunosuppressive drug DMF...

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Science Signaling Podcast for 30 August 2016: Human arginine methylome

Michael Nielsen describes the extent and importance of arginine methylation in the human proteome.

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Science Signaling Podcast for 2 August 2016: Patient-specific protein complexes

Adam Schrum and Steven Neier describe a technique for identifying patient-specific protein...

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Science Signaling Podcast for 12 July 2016: Adaptor proteins limit signaling

Steven Wiley describes a quantitative study that shows that adaptor proteins, not core signaling...

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Science Signaling Podcast for 21 June 2016: MET and skin cancer

Stuart Yuspa explains how increased signaling through the tyrosine kinase receptor MET promotes...

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Science Signaling Podcast for 21 June 2016: Nanoparticles to treat type 1 diabetes

Francisco Quintana describes nanoparticles that inhibit the development of type 1 diabetes in...

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Science Signaling Podcast for 7 June 2016: Modeling Signal Integration

Kevin Janes explains how a statistical modeling approach was used to discover how insulin...

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Science Signaling Podcast for 24 May 2016: Designer Estrogens

Benita Katzenellenbogen, John Katzenellenbogen, and Zeynep Madak-Erdogan explain how designer...

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Science Signaling Podcast for 10 May 2016: PKCalpha in Alzheimer’s disease

Alexandra Newton and Rudolph Tanzi explain how activating mutations in a kinase are linked to the...

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Science Signaling Podcast for 3 May 2016: Innate Lymphoid Cell Plasticity

.Rachel Golub and Eric Vivier discuss signaling events that control the plasticity of Group 3...

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Science Signaling Podcast for 12 April 2016: G proteins in auriculo-condylar syndrome

.Mikel Garcia-Marcos explains how mutations in a G protein subunit cause auriculo-condylar syndrome.

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Science Signaling Podcast for 22 March 2016: Preventing heart failure with GRK2

Sarah Schumacher and Walter Koch explain how a GRK2-derived peptide reduces pathological cardiac...

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Science Signaling Podcast for 15 March 2016: An inflammatory peptide in blood vessels

Giovanna Tosato explains how a cytokine subunit activates inflammatory signaling inside...

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Science Signaling Podcast for 8 March 2016: Calcium signaling and ROS in monocytes

Ivan Bogeski explains how redox-insensitive ORAI calcium channels enable monocytes to sustain...

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Science Signaling Podcast for 23 February 2016: G proteins in neutrophil migration

Alan Smrcka explains the distinct contributions that different heterotrimeric G protein subunits...

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Science Signaling Podcast for 9 February 2016: Transendothelial migration

Claus Jrgensen describes how his group used phosphoproteomic analysis to identify signaling...

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Science Signaling Podcast for 2 February 2016: Engulf and KIll

Jim Casanova describes how a machrophage adhesion receptor both mediates phagocytosis of bacteria...

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Science Signaling Podcast for 12 January 2016: GPCR heteromers and schizophrenia

Javier González-Maeso explains how ligand binding to one member of a heteromeric GPCR complex can...

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